EACS 2019 – Prevalence and outcomes of pregnancy: a 20 year long journey in Europe


  • Cristina Ferrario — Agenzia Zoe
  • Conference Reports
Access to the full content of this site is available only to registered healthcare professionals. Access to the full content of this site is available only to registered healthcare professionals.

Takeaway

  • Pregnancy reported for 1 in 5 women in EuroSIDA.
  • Substantial differences among regions, with higher prevalence in Eastern Europe.
  • Further surveillance among women living with HIV (WLWH) in Europe warranted.

Why this matters?

  • Fertility rates and birth outcomes indicate improvements in the health of WLWH in Europe, but uncertainty remains on pregnancy rates and outcomes.
  • These data could help inform equal access to care.

Study design

  • EuroSIDA: prospective, observational cohort study; over 22,000 HIV+ individuals, 35 European countries, Israel and Argentina.
  • Information on pregnancy collected from 1996-2015 as annual cross-sectional audits of pregnancy and outcomes.
  • Analysis of women aged 16 years or older and

Key results

  • Pregnancy information available for 76.2% of 5535 women included.
  • 1315 pregnancies reported: 24.3% between 1996-2002, 43.8% between 2003-2009 and 31.9% between 2010-2015.
  • The highest proportion of women with pregnancies was observed in East Europe (28.1%).
  • As for all 5 European regions, the proportion of women with a pregnancy decreased from 2003-2009 (17.3%) to 2010-2015 (12.6%).
  • Odds of pregnancy: lower in 1996-2002, in South, Central-East and East Europe, in older women, women with low CD4 counts or previously diagnosed with an AIDS-defining condition; higher in women with a previous pregnancy or HCV-positive
  • Pregnancy outcomes for 999 pregnancies (1996-2014): live births (69%), with 49.5% of them HIV-negative, 3.3% HIV-positive and 47.1% with unknown HIV status.
  • 7 stillbirths, 103 spontaneous and 199 medical abortions.

Limitations

  • Not a longitudinal follow-up.
  • Limited information on birth outcomes.
  • Differences among countries in the proportion of women with pregnancy information available.
  • Few non-white individuals.