EACS 2019 – Prevalence and outcomes of pregnancy: a 20 year long journey in Europe

  • Cristina Ferrario — Agenzia Zoe
  • Conference Reports
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  • Pregnancy reported for 1 in 5 women in EuroSIDA.
  • Substantial differences among regions, with higher prevalence in Eastern Europe.
  • Further surveillance among women living with HIV (WLWH) in Europe warranted.

Why this matters?

  • Fertility rates and birth outcomes indicate improvements in the health of WLWH in Europe, but uncertainty remains on pregnancy rates and outcomes.
  • These data could help inform equal access to care.

Study design

  • EuroSIDA: prospective, observational cohort study; over 22,000 HIV+ individuals, 35 European countries, Israel and Argentina.
  • Information on pregnancy collected from 1996-2015 as annual cross-sectional audits of pregnancy and outcomes.
  • Analysis of women aged 16 years or older and

Key results

  • Pregnancy information available for 76.2% of 5535 women included.
  • 1315 pregnancies reported: 24.3% between 1996-2002, 43.8% between 2003-2009 and 31.9% between 2010-2015.
  • The highest proportion of women with pregnancies was observed in East Europe (28.1%).
  • As for all 5 European regions, the proportion of women with a pregnancy decreased from 2003-2009 (17.3%) to 2010-2015 (12.6%).
  • Odds of pregnancy: lower in 1996-2002, in South, Central-East and East Europe, in older women, women with low CD4 counts or previously diagnosed with an AIDS-defining condition; higher in women with a previous pregnancy or HCV-positive
  • Pregnancy outcomes for 999 pregnancies (1996-2014): live births (69%), with 49.5% of them HIV-negative, 3.3% HIV-positive and 47.1% with unknown HIV status.
  • 7 stillbirths, 103 spontaneous and 199 medical abortions.


  • Not a longitudinal follow-up.
  • Limited information on birth outcomes.
  • Differences among countries in the proportion of women with pregnancy information available.
  • Few non-white individuals.