- Early-stage ovarian cancer has a good prognosis.
- Conservative vs radical surgery shows no significant survival difference.
- High-risk disease has worse prognosis irrespective of surgery type.
Why this matters
- Young women with early-stage disease who want to preserve their fertility can be offered conservative surgery.
- Study of 182 women with early-stage ovarian cancer who underwent radical (n=148) or conservative (n=34) procedures.
- Funding: None disclosed.
- Median follow-up duration was 175 months.
- 10-year DFS, OS, and cancer-specific survival, respectively:
- Total group: 82.9%, 87.9%, and 92.8%.
- Conservative surgery: 79.4%, 94.1%, and 94.1%.
- Radical surgery: 83.7%, 86.4%, and 92.5%.
- Women undergoing conservative vs radical treatment had similar DFS (P=.783) and OS (P=.334).
- In propensity-score matched analysis, no difference was observed in 10-year DFS (P=.663) and OS (P=.542) between treatments.
- Women with high risk vs low risk had worse OS (P=.007).
- Both approaches were associated with similar DFS (P=.121) and OS (P=.781).
- Single-center, retrospective.