ED tied to undiagnosed prediabetes

  • Boeri L & al.
  • J Sex Med
  • 1 Aug 2018

  • curated by Craig Hicks
  • Clinical Essentials
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Takeaway

  • 1 in 5 men seeking medical help for erectile dysfunction (ED) have blood glucose levels in the prediabetes range.

Why this matters

  • "Identifying [prediabetes] status in ED men is clinically relevant in order to adopt preventive strategies to attempt and reduce risk of developing [diabetes] and subsequent cardiovascular diseases," say researchers.

Study design

  • The researchers analyzed clinical and laboratory data for sexually active, consecutive patients seeking medical help for new-onset ED (n=372; mean age, 54.8 years; age range, 18-70 years; 100% white men).
  • They used descriptive statistics and logistic regression models to test the associations among clinical variables, prediabetes status, and severe ED.
  • Funding: None disclosed.

Key results

  • Overall, 86 patients (23.1%) had prediabetes blood glucose levels.
  • Men with prediabetes status had lower total testosterone, higher triglycerides, and higher total cholesterol (all P<.03>
  • Severe ED was associated with prediabetes status, after accounting for BMI, comorbidities, alcohol consumption, and cigarette smoking (OR, 3.37; P=.004).

Limitations

  • The study was retrospective, cross-sectional, and single-center.

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