Effects of MDCO-216 on plasma lipid and lipoprotein


  • Atherosclerosis
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Subjects carrying the apolipoprotein A-I Milano (apoA-IM) variant have a low incidence of cardiovascular disease despite a severe hypoalphalipoproteinemia, due to an increased cholesterol efflux capacity of apoA-IM-containing HDL. This led to the development of MDCO-216, a recombinant HDL contain...