Effects of MDCO-216 on plasma lipid and lipoprotein

Access to the full content of this site is available only to registered healthcare professionals. Register to read more
Subjects carrying the apolipoprotein A-I Milano (apoA-IM) variant have a low incidence of cardiovascular disease despite a severe hypoalphalipoproteinemia, due to an increased cholesterol efflux capacity of apoA-IM-containing HDL. This led to the development of MDCO-216, a recombinant HDL contain...