- Fat injection at specific sites on the head brought at least some relief to most patients with medication- and surgery-refractory migraine in this study.
- The authors include an algorithm for determining when to use this novel procedure.
Why this matters
- Of the 29 women in the study:
- 41.4% experienced complete pain resolution.
- 17.2% had subtherapeutic improvement.
- 13.8% worsened.
- For those who improved, mean improvement at last follow-up was:
- 39.3% fewer migraine attacks in a month (P=.035);
- 42.0% reduced pain intensity (P=.001);
- 74.4% shorter attacks (P=.219, not significant);
- 52.8% reduced migraine index score (P=.012).
- Prospective cohort study, 29 women with refractory migraine.
- Fat injections (sites included occipital, frontal) given September 2012 to January 2015, with at least 1 year of follow-up.
- Funding: None disclosed.
- Small sample, not randomized.