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Clinical Summary

First-trimester subchorionic haematoma not tied to early pregnancy loss

Takeaway

  • First-trimester subchorionic haematoma is not associated with early pregnancy loss in a high-risk population.

Why this matters

  • The incidence of first-trimester subchorionic haematomas noted on ultrasound ranges from 0.46% to 39.5%.
  • Some studies have shown an increased risk for miscarriage with first-trimester subchorionic haematoma.

Key results

  • 18.6% of cohort had a subchorionic haematoma.
  • Women with subchorionic haematoma presented at an earlier gestational age, possibly because of concerns about vaginal bleeding.
  • No association was seen between subchorionic haematoma and pregnancy loss before 20 weeks: aOR, 1.13 (95% CI, 0.74-1.74).
  • No association was identified between subchorionic haematoma volume, diameter, or vaginal bleeding with pregnancy loss before 20 weeks, but authors say that this analysis may be underpowered.

Study design

  • Retrospective cohort study.
  • Women who presented for prenatal care at a single maternal-foetal medicine practice before 14 weeks gestation were included (n=2586).
  • Ultrasound findings were examined for presence, size, and number of subchorionic haematomas.
  • Funding: None.

Limitations

  • Small sample size.
  • Pregnancy outcomes past 20 weeks were included.

References


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