Takeaway
- First-trimester subchorionic haematoma is not associated with early pregnancy loss in a high-risk population.
Why this matters
- The incidence of first-trimester subchorionic haematomas noted on ultrasound ranges from 0.46% to 39.5%.
- Some studies have shown an increased risk for miscarriage with first-trimester subchorionic haematoma.
Key results
- 18.6% of cohort had a subchorionic haematoma.
- Women with subchorionic haematoma presented at an earlier gestational age, possibly because of concerns about vaginal bleeding.
- No association was seen between subchorionic haematoma and pregnancy loss before 20 weeks: aOR, 1.13 (95% CI, 0.74-1.74).
- No association was identified between subchorionic haematoma volume, diameter, or vaginal bleeding with pregnancy loss before 20 weeks, but authors say that this analysis may be underpowered.
Study design
- Retrospective cohort study.
- Women who presented for prenatal care at a single maternal-foetal medicine practice before 14 weeks gestation were included (n=2586).
- Ultrasound findings were examined for presence, size, and number of subchorionic haematomas.
- Funding: None.
Limitations
- Small sample size.
- Pregnancy outcomes past 20 weeks were included.
References
References