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Fruit consumption may lower the risk for postmenopausal osteoporosis

Regular consumption of fruits may reduce the risk for postmenopausal osteoporosis (PMOP), a new meta-analysis published in the journalFood & Functionsuggests.

Researchers conducted a meta-analysis of 18 observational studies (cross-sectional, 13; case-control, 5) involving 12,643 participants, identified through a literature search on PubMed, Web of Science, and other databases.

Compared with lowest consumption, highest consumption of fruit (OR, 0.68; 95% CI, 0.56-0.83) and vegetable (OR, 0.87; 95% CI, 0.65-1.16) was associated with a decreased risk for PMOP in both case-control and cross-sectional studies. On subgroup analysis, fruit consumption was inversely associated with the risk for PMOP in case-control studies (OR, 0.52; 95% CI, 0.35-0.77) and cross-sectional studies (OR, 0.73; 95% CI, 0.59-0.89). A subgroup analysis showed a significant inverse association between vegetable consumption and risk for PMOP in case-control studies (OR, 0.62; 95% CI, 0.42-0.90), but not in cross-sectional studies (OR, 0.95; 95% CI, 0.69–1.29).

“Further research is warranted to assess the beneficial effect of specific types of fruit on the risk for PMOP and to determine the mechanisms underlying the effect of fruit on specific bone sites,” the authors said.


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