- Diagnosis of gestational diabetes mellitus (GDM) was associated with an increased risk for depression during pregnancy.
Why this matters
- Findings suggest that women with GDM should be regularly screened for depression and referred for counselling because of the harmful effect of depression on the foetal and maternal outcome.
- A prospective multi-part survey included 562 pregnant women (46 with GDM and 516 without GDM) based on their clinical obstetrical outcomes.
- Funding: None disclosed.
- Pregnant women with GDM vs those without GDM were at increased risk for depression (15.2% vs 6.2%; P=.021).
- No significant difference was observed in the history of prior (P=.362) and post-partum (P=.361) depression between pregnant women with GDM vs those without GDM.
- According to the regression model for the diagnosis of depression, the risk for depression was higher in women with GDM vs those without GDM (adjusted OR [aOR], 2.46; 95% CI, 1.01-6.03; P=.049).
- Pre-pregnancy body mass index was associated with the diagnosis of depression (aOR, 1.06; 95% CI, 1.01-1.11; P=.015).
- Small sample size.
- Lack of specific diagnostic criteria for depression.