- The risk for traveller's diarrhoea (TD) is significantly reduced for international travellers supplied with alcohol-based hand sanitising gel and instructions on when and how to use it.
Why this matters
- TD causes considerable economic burden and raises the risk for colonisation with extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae, contributing to antibiotic resistance.
- Researchers in this interventional trial studied the effect of hand sanitising gel on TD and ESBL-producing Enterobacteriaceae colonisation in travellers to Southeast Asia (N=222; median age, 38 years; 53.2% women).
- They randomly assigned travellers to a comparator group given standard pretravel health advice or an intervention group given additional information on how to use supplied hand sanitising gel: before eating or after toilet use, with a volume that keeps hands wet for at least 30 seconds.
- Funding: IVF Hartmann AG.
- Intent-to-treat analysis showed a protective effect against TD in the intervention group (OR, 0.54; 95% CI, 0.30-0.97; P=.04).
- There was no effect on incidence of ESBL-producing Enterobacteriaceae colonisation.
- Travellers in both groups used hand sanitiser, significantly reducing the study’s statistical power.
- Results may not apply to other travel destinations.