- Heart failure (HF) is less common among patients with type 2 diabetes (T2D) than stroke, chronic kidney disease (CKD), or peripheral artery disease (PAD) but is more lethal.
- Findings highlight importance of HF monitoring in patients with T2D.
Why this matters
- Few data are available about mortality risk for different cardiovascular (CV) and renal diagnoses in patients after T2D diagnosis.
- From Danish nationwide registers, the study population included 153,405 patients with newly diagnosed T2D during 1998-2015 and no prior CV or renal diagnosis.
- Funding: Danish Heart Association; Boehringer Ingelheim.
- During median 9.7-year follow-up, 45.1% (69,201) received a CV or renal diagnosis, including 12.6% ischemic heart disease (IHD), 4.7% stroke, 4.1% CKD, 3.0% PAD, and 2.2% HF.
- Death risk within 5 years of T2D diagnosis was highest for those with HF (47.6%) vs those with PAD (37.1%), stroke (34.5%), CKD (27.7%), IHD (21.0%), and no other diagnosis (15.9%), respectively.
- Compared with those not developing CV disease or CKD, reduced lifespan (in months; 95% CIs) with:
- HF: 11.7 (11.6-11.8).
- IHD: 1.6 (1.5-1.7).
- Stroke: 6.4 (6.3-6.5).
- CKD: 4.4 (4.3-4.6).
- PAD: 6.9 (6.8-7.0).
- Lack of information on clinical factors reflecting HF and T2D severity, microvascular complications.