- This meta-analysis suggests that the prevalence of obstructive sleep apnoea (OSA) is higher in women with polycystic ovary syndrome (PCOS) and obesity.
Why this matters
- Findings suggest that physicians should have a high index of suspicion of OSA in women with PCOS.
- 17 studies involving 648 participants met the eligibility criteria after a search on MEDLINE, Embase, CINAHL, PsycINFO, Scopus, Web of Science, and other electronic databases.
- Funding: None disclosed.
- The pooled prevalence of OSA was 35.0% (95% CI, 22.2-48.9%; I2, 92%) in women with PCOS.
- Women with PCOS were 4 times more likely to develop OSA vs control participants (8 studies [n=957]; OR, 3.83, 95% CI, 1.43-10.24).
- The prevalence of OSA was 38% higher in women with obesity vs non-obese women with PCOS (2 studies; prevalence difference, +37.9%, 95% CI, 15.0-60.9%).
- Heterogeneity among included studies.
- Risk of selection bias.