- Improved treatment access and use lead to reduced risk engagement after HIV seroconversion in men who have sex with men (MSM).
Why this matters
- Continued investment in HIV care linkage/care continuum is essential to reduce specific risky behavior in HIV-infected persons generally, and in MSM specifically.
- 558 MSM seroconversions.
- HIV seroconversion associated with reduced odds of risky behavior, including: 1) subsequent engagement of sex with >2 partners (aOR, 0.371; 95% CI, 0.263-0.523), 2) insertive anal sex with >2 partners (aOR, 0.360; 95% CI, 0.219-0.591), 3) heavy drinking (aOR, 0.704; 95% CI, 0.508-0.977).
- Post-1996 highly active antiretroviral therapy (HAART) seroconversions linked to further reduced odds of insertive anal sex with >2 partners (aOR, 0.219; 95% CI, 0.121-0.398) vs pre-1996 (aOR, 0.411; 95% CI, 0.241-0.703).
- Post-HIV treatment seroconversion associated with further reduced odds of any sex with >2 partners (aOR, 0.239; 95% CI, 0.157-0.364) in post- vs pre-1996 (aOR, 0.392; 95% CI, 0.276-0.557).
- Prospective cohort evaluating the association of HIV seroconversion, treatment with subsequent health behaviors during US HAART expansion.
- Funding: National Institute on Drug Abuse.
- Racial/ethnic minority under-representation.
- Data precede "treatment as prevention."
- Reporting bias, subjective responses.
- No comparison of long-term vs newly infected.