Hodgkin lymphoma detection and survival in the UK

  • Lamb MJ & al.
  • BJGP Open
  • 10 Dec 2019

  • curated by Dawn O'Shea
  • UK Medical News
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One in five patients diagnosed with classical Hodgkin lymphoma (CHL) suffers delays in diagnosis, according to a new study which examined the relationship between markers of advanced disease, emergency admission and survival following a diagnosis.

The study was set within a sociodemographically representative UK population-based patient cohort of approximately 4 million. Patients were tracked through their care pathways and linked to national data obtained from Hospital Episode Statistics and deaths.

A total of 971 patients with CHL newly diagnosed between 1 September 2004-31 August 2015 were followed until 18 December 2018.

Within the cohort, median age at the time of diagnosis was 41.5 (range, 0-96) years. More than half (55.2%) were male, 31.2 per cent had stage IV disease, 43.0 per cent had a moderate- to high- or high-risk prognostic score and 18.7 per cent were admitted via the emergency route.

Those presenting as an emergency had more advanced disease and poorer three-year survival (relative survival, 68.4% vs 89.8%; P<.01 however after adjusting for clinically important prognostic factors no difference in survival remained.>

Presenting the findings in BJGP Open, the authors said the findings suggest that CHL survival could be increased by around 4 per cent if the cancer in patients who presented as an emergency had been detected at the same point as in other patients.