- The risk of hypertension associated with hypertensive disorders of pregnancy is high immediately after an affected pregnancy and persists for more than 20 y.
Why this matters
- Hypertensive disorders of pregnancy (pre-eclampsia; eclampsia; haemolysis, elevated liver enzymes, and low platelets (HELLP) syndrome; and gestational hypertension) affect up to 10% of pregnancies.
- Compared with 4% of women with normotensive first pregnancies in their 20s, 14% of women with a hypertensive disorder of pregnancy in a first pregnancy developed hypertension in the first-decade post partum.
- The corresponding percentages for women with a first pregnancy in their 40s were 11% and 32%, respectively.
- The rates of post-pregnancy hypertension were 12-fold to 25-fold higher in women with a hypertensive disorder of pregnancy than in women with a normotensive pregnancy.
- The rates were 3 to 10-fold higher in the decade after delivery and remained twice as high even 20 or more years later.
- 482972 women with no hypertension with a first live birth or stillbirth between 1995 and 2012 were included for cumulative incidence analyses.
- 1025118 women with at least one live birth or stillbirth between 1978 and 2012 were included for Cox regression analyses.
- Funding: Danish Council for Independent Research, Danish Heart Association.