HPV vaccine: series completion rates lowest among blacks, Hispanics

  • Freeman AJH & al.
  • Obstet Gynecol
  • 6 Aug 2018

  • curated by Liz Scherer
  • Clinical Essentials
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  • Despite having the same health care coverage, >50% of female members of an integrated health system who initiated the HPV vaccine did not complete the series.
  • Lowest completion rates were seen in black and Hispanic patients.

Why this matters

  • Despite having the highest cervical cancer incidence and mortality rates, Hispanic and black women are less likely than their white peers to receive an initial vaccine recommendation.
    • HPV vaccine initiation and series completion should be targeted during routine office visits.

Key results

  • 102,052 females (ages, 11-26 years) initiated HPV series in the final cohort:
    • 27.5% (n=28,024) Hispanic, 36.4% (n=37,109) white, 18.7% (n=19,129) Asian or Pacific Islander, 9.8% (n=9965) black.
  • 41.0% (41,847/102,052) completed the series, with highest completion rates seen in Asian/Pacific Islanders (49.5%), lowest among blacks (28.7%; P<.001 style="list-style-type:circle;">
  • 38.9% of Hispanics completed series.
  • Odds of vaccine completion were 47% and 18% lower among blacks and Hispanics, respectively, than whites (P<.001>
  • Age-adjusted odds ratio for vaccine completion (≥2 doses) was 1.29 low vs high acculturated patients (95% CI, 1.29-1.38).
  • Study design

    • Retrospective cohort analysis comparing female HPV vaccine completion rates by race and ethnicity in an integrated health care system.
    • Funding: Kaiser Permanente, Northern California.


    • Retrospective.
    • Limited Hispanic acculturation definition, data, completion rates.
    • Limited generalizability.

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