HPV vaccine: uptake higher among Hispanic vs white male adolescents

  • Landis K & al.
  • Vaccine
  • 8 May 2018

  • curated by Liz Scherer
  • Clinical Essentials
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  • 2014 National Immunization Survey (NIS)-Teen data show that Hispanic, non-Hispanic "other" male adolescents have 76% higher odds of initiating HPV vaccination compared with white peers.
  • Adolescents up-to-date on tetanus, diphtheria, acellular-pertussis vaccine Tdap, or meningococcal vaccines have significantly higher odds for HPV vaccine initiation and provider recommendations.

Why this matters

  • HPV vaccine initiation remains low in adolescent males, demonstrating that providers need to be more proactive in offering and encouraging vaccine uptake.
  • Bundling HPV vaccine with Tdap, meningococcal vaccinations during provider visits may improve initiation in adolescent males.

Key results

  • Overall, 41.3% (4436/10,743) male adolescents initiated the HPV vaccine.
  • 53.7% of parents self-reported having received a provider recommendation.
  • 75.3% of adolescents were up-to-date on either Tdap or meningococcal vaccines.
  • 54.2%, 36.4% Hispanic, non-Hispanic whites, respectively, initiated the HPV vaccine.
  • Compared with non-Hispanic whites, Hispanic adolescents, non-Hispanic "other" or multiple races had 76% (OR, 1.76; 95% CI, 1.32-2.34), 43% (OR, 1.43; 95% CI, 1.05-1.96) odds, respectively, for initiating HPV vaccine.

Study design

  • Retrospective cohort analysis (2014 National Immunization Survey-Teen) to examine racial/ethnic differences in HPV vaccine initiation and provider recommendations for adolescent males.
  • Funding: NIH.


  • Self-report, responder(s) bias.
  • Exposure confounder.
  • Estimates not applicable to prior surveys.

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