- In patients with hypertension, hypothyroidism is associated with increased risk for hypertensive intracerebral hemorrhage (ICH), according to a case-control study.
Why this matters
- Identifying risk factors can assist prevention and treatment of hypertensive cerebral hemorrhage.
- Hypothyroidism was present in 23.4% of patients with hypertensive ICH and 14.3% of matched control individuals with hypertension.
- Hypothyroidism was associated with increased risk for hypertensive ICH in multivariate analysis (OR, 2.29 [P=.001]; OR, 1.92 [P=.016] in separate propensity score matching analysis).
- Male sex (OR, 2.11; P<.05 and diabetes p=".037)" were also associated with increased risk for hypertensive ich whereas hyperlipidemia appeared to exert a protective effect>
- 462 patients, 231 with hypertensive ICH and 231 with hypertension, were analyzed for the prevalence of hypothyroidism.
- 179 patients with hypertensive ICH and 179 control individuals were included in the propensity-matched analysis.
- Funding: None disclosed.
- Retrospective study design.