- A pair of BP studies in young adults in the United States (ages 18-30 years) and Korea (ages 20-39 years) yielded some remarkably similar findings:
- About 1 in 2 young adults has abnormal BP.
- BP >120/80 mmHg is tied to risk for early cardiovascular disease (CVD).
- Those with higher BP usually had other CVD risk factors, too.
- Absolute CVD event rates were low.
Why this matters
- Both studies assessed whether hypertension in young adults, defined in 2017 American College of Cardiology/American Heart Association guidelines, is tied to increased CVD events.
- Accompanying editorial says the overall body of evidence indicates a need to begin primary prevention of hypertension during childhood.
- US study, with median 18.8-year follow-up; incidence rates per 1000 person-years and HRs vs normal BP (95% CIs) by BP category:
- Normal: 1.37.
- Elevated: 2.74; 1.67 (1.01-2.77).
- Stage 1 hypertension: 3.15; 1.75 (1.22-2.53).
- Stage 2: 8.04; 3.49 (2.42-5.05).
- Korean study, median 10-year follow-up; adjusted HRs (95% CIs) for CVD event vs normal BP:
- Stage 1 hypertension, men: 1.25 (1.21-1.28).
- Stage 1 hypertension, women: 1.27 (1.21-1.34).
- US: prospective cohort study, n=4851.
- Outcome: CVD events.
- Funding: NIH, others.
- Korean study: national cohort, n=2,488,101.
- Outcome: CVD (2+ days in hospital for CVD or CVD mortality).
- Funding: Korean government.
- No adjustment for change in BP category over time.
- BP measurement not always according to recommendations.