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Clinical Summary

Hypertension: inconsistency in clinical practice guidelines

Takeaway

  • Clinical practice guidelines for assessing and managing hypertension have a “high rate of inconsistency”, according to findings from this cross-sectional study.
  • These authors say that no single source underlies areas of inconsistency among the 8 guidelines they examined.

Why this matters

  • These authors say that these guidelines are “poor proxies for a universally accepted source of truth.”
  • They say that the focus should be on classifying consistency across guidelines as a signpost for clinical practice.

Key results

  • Among the 8 guidelines evaluated:
    • 22 (32%) recommendations were consistent with each other for both strength and direction.
    • 18 (26%) were consistent for direction but not strength (e.g., when to use ambulatory BP monitoring).
    • 28 (41%) were inconsistent for direction (e.g., cutoffs for hypertension).
  • 17 of 48 (35%) recommendations considered of high importance showed inconsistency of direction.
  • Various analyses excluding recommendations with specific evidence ratings did not pinpoint a sole source of inconsistency.

Study design

  • 8 guidelines included, from the United States, Australia, Canada, Europe, the UK.
  • 71 recommendations were evaluated.
  • Funding: EBSCO Information Services.

Limitations

  • The authors had to create a method for evaluating consistency.
  • They dichotomised strength ratings.

References


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