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Clinical Summary

Hypertension: vertigo ups the risks for stroke-related mortality

Takeaway

  • Patients with hypertension who experience vertigo are at higher risks for stroke mortality compared to those without dizziness or patients with dizziness other than vertigo.

Why this matters

  • 0.2%-3.4% of patients hospitalised for stroke-related events have reported symptoms such as dizziness or vertigo.
  • European guidelines recommend looking out mainly for such symptoms which may be related to organ damage.
  • The prognostic importance of vertigo in hypertension prompts the need for multidisciplinary management among patients with vertigo and hypertension.

Study design

  • A total of 1716 patients with hypertension were identified from the OLD-HTA Lyon’s cohort (1970’s); patients were followed for 30 years.
  • Funding: None disclosed.

Key results

  • Of the 33.9% patients who had dizziness, the subtypes presented were vertigo (n=110), hypotension-like dizziness (n=168), motion sickness dizziness (n=300), and other dizziness (n=184).
  • 956 deaths were reported, of which 508 were cardiovascular cause and 114 with fatal acute strokes as the cause.
  • Increased risks for stroke mortality were reported in patients with:
    • vertigo vs no dizziness (aHR, 2.43; P=.004) and
    • vertigo vs dizziness excluding vertigo (aHR, 2.22; P=.010).
  • Dizziness was not associated with risks for stroke mortality (aHR, 1.27; P=.247).

Limitations

  • Potential recall bias.
  • Chances of misclassification of dizziness.

References


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