- Key risk factors for hepatocellular carcinoma (HCC) often are overlooked in low-middle income regions, according to this study involving 55 HIV clinic sites in 31 countries.
Why this matters
- Liver cancer is the fourth leading cause of cancer death worldwide.
- Hepatitis virus infections are a main cause, with HBV and HCV as the etiology in 60% of cases.
- Coinfection with HBV/HCV and HIV is common.
- Only 5% of sites were in high-income regions.
- Serological testing for HBV/HCV infections is generally available but rarely performed routinely in African countries.
- Routine testing for HBV/HCV showed large regional variation (HBV: 22%-100%; HCV: 0%-80%), including in high-burden countries.
- Less than 25% of sites assessed HBV viral load.
- Only 5 sites had an ongoing HCV screening program.
- 53% of sites routinely assessed alcohol consumption.
- Researchers analyzed data on testing and management of liver-related disease and risk factors in this cross-sectional web-based survey of HIV clinics, December 2014-September 2015.
- The study was conducted mostly on tertiary nonrepresentative sites.
- Data were presented without peer review at a conference.