IAS 2019 — HCC: key risk factors are overlooked in low-middle income regions


  • Myriam Vidal Valero
  • Conference Reports
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Takeaway

  • Key risk factors for hepatocellular carcinoma (HCC) often are overlooked in low-middle income regions, according to this study involving 55 HIV clinic sites in 31 countries.

Why this matters

  • Liver cancer is the fourth leading cause of cancer death worldwide.
  • Hepatitis virus infections are a main cause, with HBV and HCV as the etiology in 60% of cases.
  • Coinfection with HBV/HCV and HIV is common.

Key results

  • Only 5% of sites were in high-income regions.
  • Serological testing for HBV/HCV infections is generally available but rarely performed routinely in African countries.  
  • Routine testing for HBV/HCV showed large regional variation (HBV: 22%-100%; HCV: 0%-80%), including in high-burden countries.
  • Less than 25% of sites assessed HBV viral load.
  • Only 5 sites had an ongoing HCV screening program.
  • 53% of sites routinely assessed alcohol consumption.

Study design

  • Researchers analyzed data on testing and management of liver-related disease and risk factors in this cross-sectional web-based survey of HIV clinics, December 2014-September 2015.

Limitations

  • The study was conducted mostly on tertiary nonrepresentative sites.
  • Data were presented without peer review at a conference.