- The risk for any and clinically significant prostate cancer was significant in men with IBD vs age- and race-matched men without IBD.
- No association was found between IBD and metastatic disease.
Why this matters
- Data on the association between prostate cancer and IBD are limited.
- Study of 1033 patients with IBD and 9306 age- and race-matched men without IBD (control group) who underwent ≥1 PSA screening test.
- Funding: None.
- Median age was 53 years in both groups.
- Median follow-up time: IBD group, 6.5 years; control group, 4.7 years.
- At 10 years, men with IBD vs those without IBD showed higher incidence of:
- prostate cancer (4.4% vs 0.65%; HR, 4.84; P<.001>
- clinically significant (Gleason score of ≥7) prostate cancer (2.4% vs 0.42%; HR, 4.04; P<.001>
- Retrospective design.