- 1 in 8 patients with IBD developed colorectal cancer (CRC) before the currently recommended period for initiating CRC screening in this population.
- Factors predicting early CRC include IBD onset before age 28 years and tobacco use.
Why this matters
- Recommendations are for CRC surveillance at 8-10 years after IBD onset.
- Average time to CRC diagnosis after IBD onset was 22.8 (standard deviation [SD], 12.5) years.
- 11.8% developed CRC before the 8-year mark after IBD onset (mean, 3.5 years; SD, 3.0 years).
- 12.8% of those under age 50 years were diagnosed with CRC in
- Risk factors for CRC
- Age >28 years: 12.0 (2.30-62.75).
- Tobacco use: 8.52 (1.38-52.82).
- Single-center, observational study, 93 patients with IBD and diagnosed with CRC.
- Those with earlier vs later CRC diagnoses were compared.
- Funding: NIH.
- Retrospective, observational, single tertiary-care center.