A recent study published in the journal Obesity investigated value of imaging-based body composition profiling (BCP) for better understanding of metabolic health. Most fat compartments were positively associated with coronary heart disease (CHD) and type 2 diabetes (T2D).
6021 participants (mean age, 62.3±7.5 years) from the UK Biobank imaging sub-study were included. MRI was used to determine abdominal subcutaneous adipose tissue, visceral adipose tissue index (VATi), thigh muscle volume, liver fat and muscle fat infiltration (MFI). Matching procedures and multivariable statistical modelling were used to determine the association between BCP and metabolic status.
In matched control analysis, higher VATi and MFI were positively associated with CHD and T2D (P<.001 lower liver fat was associated with chd whereas higher t2d in multivariable statistical modelling vati and mfi were positively negatively chd. p metabolic health. associations significant even after adjusting for sex age bmi alcohol smoking physical activity.>
Authors believe that single examination based description of an individual’s body composition enables a more standardised and detailed description of metabolic disease status. The authors say: “By combining multivariable body composition analysis with already measured biomarkers, there is potential for highly individualized intervention plans”.