- Interpregnancy weight change affects pregnancy outcomes.
Why this matters
- Interpregnancy weight change and the difference in BMI between the first and second pregnancy may predict risk for pregnancy complications.
- Women with BMI >30 kg/m2 at postpartum visits may benefit from being referred for advice on weight-loss interventions.
- A decrease of >1 BMI unit was associated with a 33% reduction in large for gestational age (LGA) births (aOR, 0.70; 95% CI, 0.55-0.90).
- An increase in BMI was associated with a higher risk for LGA births (aOR, 1.43; 95% CI, 1.29-1.59).
- An increase in BMI was associated with higher risk for cesarean delivery (CD) (aOR, 1.16; 95% CI, 1.06-1.26).
- A decrease in interpregnancy BMI was associated with a reduced risk for gestational diabetes mellitus (GDM) (aOR, 0.80; 95% CI, 0.62-1.03).
- A decrease in interpregnancy BMI was associated with an increased risk for small for gestational age (SGA) births (aOR, 1.31; 95% CI, 1.06-1.63).
- Systematic review and meta-analysis of observational and cohort studies (11 studies; n=925,065 women).
- Outcomes included LGA, SGA, macrosomia, CD, and GDM.
- Funding: None disclosed.
- Heterogeneity of studies may make it difficult to draw conclusions.
- Limited generalizability.