- Higher BMI is linked to increased severity of COVID-19 disease among patients
Why this matters
- A BMI cutoff of ≥25 might be important for risk stratification, especially in younger patients of Asian ancestry.
- 91 patients with RT-PCR-confirmed COVID-19, grouped by BMI:
- 25-30: 31.9% (29).
- 31-35: 7.7% (7).
- >35: 4.4% (4).
- With analysis including all ages, patients with BMI ≥25 vs
- Among a subgroup of patients age
- Pneumonia on chest radiograph: P=.017.
- Needing low-flow supplemental oxygen: OR, 6.32 (95% CI, 1.23-32.34).
- Needing mechanical ventilation: OR, 1.16 (95% CI, 1.00-1.34).
- Patients with BMI ≥25 also had significantly higher serum lactate dehydrogenase levels (P=.011), which have been associated with COVID-19 disease severity.
- Retrospective cohort study evaluating association between BMI and COVID-19 disease severity among patients admitted to the National Centre for Infectious Diseases, Singapore.
- Outcomes: hypoxia requiring supplemental oxygen, ICU admission, mechanical ventilation, mortality.
- Funding: NMRC COVID-19 Research Fund.
- No control.
- Limited generalizability.