- Children with Crohn’s disease have more rectal involvement and perianal disease compared with adults, based on this MRI study.
- Authors also note “apparent inaccuracy of the Montreal clinical classification” that their results suggest.
Why this matters
- The pediatric distinctions imply worse outcomes for these patients, say the authors.
- Clinicians may want to consider these differential imaging manifestations.
- Perianal disease prevalence:
- 34.6% among children.
- 16.1% among adults.
- OR for children: 2.8 (P=.0018).
- Rectal involvement prevalence:
- 29.7% among children.
- 13.5% among adults.
- OR for children, 2.7 (P=.0042).
- Children had a higher risk for perianal involvement with rectal disease (OR, 4.5; P=.0286).
- Applying the Montreal classification for lesion location failed to surface these differences.
- Retrospective review, 219 MRI studies included (118 adults; 101 children), 2013-2016.
- Fisher’s exact and ORs calculated.
- Funding: None.
- Retrospective, single-center.