- Patients with knee osteoarthritis (OA) who are inactive before exercise therapy and education achieve a similar benefit to patients with higher levels of preexisting physical activity.
Why this matters
- Exercise therapy and education are beneficial for all patients with knee OA, regardless of preexisting activity level.
- Prospective cohort study of 12,796 patients with knee OA participating in the Good Life with Osteoarthritis in Denmark.
- Intervention consisted of 12 sessions of supervised exercise and 2 sessions of education by physical therapists.
- Benefit was measured by mean change in knee pain by visual analog scale (1-100 points).
- Preexisting physical activity was stratified into 5 groups: inactive, low, moderate, high, and very high physical activity according to the University of California, Los Angeles activity scale.
- Funding: Danish Physiotherapy Association; Danish Rheumatism Association; Independent Research Fund Denmark.
- Inactive patients at baseline had worse pain compared with other activity groups (range: 6-15 points; P<.001>
- Inactive patients had a decrease in pain by 13.4 points (95% CI, 9.4-17.1 points) immediately postintervention and by 12.8 points (95% CI, 7.7-18.0 points) at 12 months postintervention.
- Magnitude of pain decrease postintervention and at 12 months was similar in the inactive vs active groups.
- Uncontrolled, nonrandomized design.