- Krill oil supplementation appears to be beneficial as it decreases cardiovascular disease risk parameters through its effects on plasma a triacylglycerol (TAGs), lipoprotein particles, fatty acid profile, redox status and possibly inflammation.
- A 28 days intervention study assessing effect-parameters of dietary supplementation with krill oil (832.5 mg EPA and DHA per day) in 17 healthy volunteers (18-36 years).
- Plasma lipids, lipoprotein particle sizes, fatty acid composition in plasma and red blood cells (RBCs), plasma cytokines, antioxidant capacity, acylcarntines, carnitine, choline, betaine, and trimethylamine-N-oxide (TMAO) were measured before and after supplementation.
- Plasma TAG and large very-low density lipoprotein & chylomicron particle concentrations decreased after participants took krill oil for 28 days
- A significant reduction in the TAG/HDL cholesterol resulted.
- Krill oil supplementation also decreased n-6/n-3 polyunsaturated fatty acids (PUFA) ratio both in plasma and RBCs, due to the increase of EPA, DHA and docosapentaenoic acid and reduced amount of arachidonic acid (AA).
- Krill oil intake increased the antioxidant capacity, double bond index and the fatty acid anti-inflammatory index.
Why This is Important
- Supplementing with krill oil may help prevent the development of a number of risk factors linked to cardiovascular disease.