- Small renal masses in elderly patients on active surveillance display indolent behavior in the long term, with a low rate of progression to metastatic disease.
- Nearly 46% of patients died of other causes.
Why this matters
- Active surveillance appears to be safe in patients at high risk for the morbidity of active treatment.
- High other-cause mortality rate throughout follow-up indicates that active treatment would not be beneficial in these patients.
- 103 patients (median age, 75 years) with 107 renal masses undergoing active surveillance of small renal masses diagnosed between 2001 and 2011.
- Median maximum diameter and volume at diagnosis were 2.1 cm and 4.8 cm3, respectively.
- Outcomes: progression to treatment, metastatic disease, and/or death.
- Funding: None disclosed.
- Median follow-up was 55.5 months.
- Disease metastasis was reported in 1.9% of patients, and 1.0% died of renal cell carcinoma.
- The mean linear and volumetric growth rates of renal masses were 0.21 cm per year and 6.15 cm3 per year, respectively.
- 51.5% of patients remained on active surveillance and 46.6% died of other causes.
- Small observational study.
- Lack of biopsy reports.