- Nearly 40% of US patients with lung cancer do not receive the treatment recommended by national guidelines.
Why this matters
- The data highlight targets for improving receipt of guideline-recommended care, including in local and advanced NSCLC and extended-disease SCLC.
- 441,812 patients with lung cancer from the National Cancer Database diagnosed between 2010 and 2014.
- Funding: National Cancer Institute.
- 62.1% received recommended treatment (from 50.4% in advanced NSCLC to 76.3% in local NSCLC).
- 16.3% received less intensive treatment than recommended (from 6.4% in extensive disease SCLC to 21.6% in locally advanced NSCLC).
- 21.6% received no treatment (from 10.3% in local NSCLC to 31.4% in advanced NSCLC).
- Receipt of recommended treatment decreased with advancing age (age, ≥80 years vs
- Among patients with local NSCLC, older patients were less likely to undergo surgery (aOR, 0.06; 95% CI, 0.05-0.06) and more likely to receive stereotactic body radiation therapy (aOR, 18.39; 95% CI, 14.09-23.99).
- Compared with whites, receipt of recommended treatment was less likely in non-Hispanic blacks (aOR, 0.78; 95% CI, 0.76-0.80) and Hispanics (aOR, 0.94; 95% CI, 0.90-0.98), and more likely among non-Hispanic Asians (aOR, 1.09; 95% CI, 1.04-1.15).
- Only first course of treatment considered.