- Young adults with higher Mediterranean diet score or A Priori Diet Quality Score (APDQS) had slower decline in cognition during the next 3 decades.
Why this matters
- Attractiveness of lifestyle interventions to prevent dementia.
- Dietary Approaches to Stop Hypertension (DASH) diet not associated with change in cognitive performance.
- Higher Mediterranean diet score tertile associated with less decline in composite cognitive function (P=.03), Stroop Interference (P<.01 style="list-style-type:circle;">
- Low: −0.04, 0.09.
- Middle: 0.03, −0.06.
- High: 0.03, −0.03.
- Mediterranean diet: 0.54 (95% CI, 0.39-0.74).
- APDQS: 0.48 (95% CI, 0.33-0.69).
- DASH: 0.89 (95% CI, 0.68-1.17).
- Prospective cohort study, 2621 participants in CARDIA.
- Diet scores from diet history: baseline (mean age, 25 years), year 7 (mean age, 32 years), year 20 (mean age, 45 years).
- Cognitive function: year 25 (mean age, 50 years), year 30 (mean age, 55 years).
- Main outcome: change in composite cognitive function at year 30.
- Funding: American Federation of Aging Research; others.
- Olive oil not considered in Mediterranean diet score.
- Residual confounding.
- Unclear generalizability.