- A retrospective study suggests that tumor thickness and mitotic number are associated with outcomes following surgical treatment in patients with malignant melanoma.
Why this matters
- Better understanding of risk factors can help guide patient management.
- 22.7% of patients developed distant metastasis and 9.41% developed local recurrence.
- Tumor thickness (aHR, 6.139; P=.001) and increased mitotic number (aHR, 4.483; P=.023 for 2-6 vs 0-1/mm2; aHR, 10.316; P<.001 for>6 vs 0-1/mm2) were associated with increased risk of distant metastasis in multivariate analysis.
- Tumor thickness (aHR, 8.461; P=.001) was associated with increased risk of local recurrence in multivariate analysis.
- 202 patients with malignant melanoma who underwent surgical excision were analyzed for risk factors for distant metastasis and local recurrence.
- Funding: None.
- Retrospective study.