Meta-analysis: panic disorder, OCD more common in pregnancy

  • Viswasam K & al.
  • J Affect Disord
  • 11 May 2019

  • International Clinical Digest
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Takeaway

  • Prevalence of panic disorder (PD) and obsessive compulsive disorder (OCD) during pregnancy was higher than the lifetime prevalence among the general population, according to a meta-analysis of anxiety disorders during pregnancy.
  • Although general anxiety disorder and social anxiety disorder were common in pregnant people, the prevalence was lower than or similar to the lifetime prevalence among the general population.

Why this matters

  • This study provided missing information by not only analyzing the prevalence of all anxiety disorders but also limiting the analysis to pregnancy only.

Study design

  • Meta-analysis of 36 eligible studies identified after a search in Google Scholar, MEDLINE, EMBASE, PsychINFO, PubMed, and ProQuest.
  • Funding: None disclosed.

Key results

  • In pooled data analysis, PD, OCD, GAD, and social anxiety disorder prevalence rates during pregnancy were 3% each (all P<.001>
  • The overall prevalence of specific phobia was 6% (P<.001>
  • During pregnancy, prevalence rates of PD and OCD were higher (1.6% each), whereas GAD and social anxiety disorder prevalence rates were lower or similar to lifetime rates in general population (8.4% and 2.9%, respectively).
  • 13%-39% of all cases of OCD had an onset of OCD during pregnancy, mainly during the second semester.

Limitations

  • Heterogeneity across studies.

Coauthored with Antara Ghosh, PhD