- After adjusting for covariates, neither poor metabolic health nor obesity was associated with risk for depressive symptoms at the end of 2-year follow-up in a prospective study of English population.
- Lower wealth and baseline depression were strong predictors of risk for depressive symptoms at 2-year follow-up.
Why this matters
- Previous reports examining associations between metabolic health, obesity and depression are conflicting.
- Wealth inequalities continue to rise across England.
- Prospective study evaluated 6804 participants (mean age, 67.6 years) who participated in English Longitudinal Study of Ageing Wave 6 (2012-2013) and Wave 7 (2014-2015).
- A score ≥4 in Center for Epidemiologic Studies Depression depicted elevated depressive symptoms.
- Presence of ≥2 metabolic risk factors defined poor metabolic health.
- Funding: None disclosed.
- At follow-up, 12.5% participants had elevated depressive symptoms.
- After adjusting for covariates, no association was observed between poor metabolic health and depressive symptoms (aOR, 1.17; P=.07).
- Similarly, obesity was not associated with depressive symptoms after adjusting for covariates (aOR, 1.19; P=.06).
- Individuals in the highest vs lowest (aOR, 0.31; P<.01 wealth quintiles were less likely to experience depressive symptoms.>
- Baseline depression (aOR, 10.59; P<.01 was a strong predictor of future depression.>
- Findings generalisable to the English population.
- Only respondents aged >50 years were included.