- Migraine headaches are not associated with consumption of ≤2 daily servings of caffeinated beverages among patients who regularly consume ≥1 servings/day.
Why this matters
- Few prospective studies have examined the association between caffeine consumption and migraine risk.
- Prospective cohort study of 98 adults with episodic migraine who provided detailed information on daily caffeinated beverage intake for at least 6 weeks.
- Funding: National Institute of Neurological Disorders and Stroke; others.
- Overall, 825 headaches were reported over the course of 4467 days, with an average of 8.4 headaches/participant.
- The average consumption of caffeinated beverages was 7.9 servings/week on an average of 4.5 days/week.
- A significant nonlinear association was noted between the number of caffeinated beverages and the odds for migraine headache occurrence (P quadratic trend=.024).
- Consumption of 1-2 servings of caffeinated beverage was not associated with increased odds for headache.
- Higher odds for headaches were estimated on days with ≥3 servings of caffeinated beverages.
- With ≥3 servings there was a higher trend for headaches on the following day (not significant).
- The heightened risk could not be associated with the amount of caffeine consumed.
Coauthored with Chitra Ravi, MPharm.