Migraine patients have higher risk for insomnia, anxiety, and depression

  • Kim KM & al.
  • Sci Rep
  • 20 Dec 2019

  • International Clinical Digest
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Takeaway

  • People with a history of migraines are significantly more likely to have self-reported insomnia, anxiety, or depression compared with those without a migraine history. 
  • Those with both migraine and insomnia histories have an even higher risk of anxiety and depression.

Why this matters

  • Clinicians working with migraine patients who report insomnia might consider screening for anxiety and depression.

Study design

  • Data of 2695 participants from a nationwide population-based survey on headache and sleep, the Korean Headache-Sleep Study.
  • Funding: Korean government.

Key results

  • 5.3% of participants had migraine.
  • 9.9% of participants had anxiety, 4.3% had depression, and 9.4% had self-reported insomnia.
  • Participants with migraine vs no migraine had higher prevalence of:
    • Self-reported insomnia: 21.7% vs 8.7% (P<.001>
    • Anxiety: 30.1% vs 8.8% (P<.001 and>
    • Depression: 16.8% vs 3.6% (P<.001>
  • Participants with migraine and self-reported insomnia had higher risk for:
    • Anxiety: OR, 7.0 (95% CI, 3.0-16.7); and
    • Depression: OR, 3.3 (95% CI, 1.3-8.5).

Limitations

  • Survey-based data.

Coauthored with Chitra Ravi, MPharm