Milk, dairy consumption fail to reduce osteoporosis, hip fracture in meta-analysis

  • Malmir H & al.
  • Crit Rev Food Sci Nutr
  • 26 Mar 2019

  • International Clinical Digest
Access to the full content of this site is available only to registered healthcare professionals. Access to the full content of this site is available only to registered healthcare professionals.

Takeaway

  • A meta-analysis concludes that milk and total dairy consumption is not associated with reduced risk for osteoporosis or hip fracture.
  • Methodologically stronger cohort studies found no associations, whereas weaker cross-sectional and case-control studies had some positive, but inconsistent, findings.

Why this matters

  • This is one of the first meta-analyses of its kind to tackle conflicting literature.

Study design

  • Meta-analysis of 34 studies after a search of PubMed, Web of Science, EMBASE, SCOPUS, and Google Scholar.
  • Funding: Tehran University of Medical Sciences.

Key results

  • Cohort studies:
    • Milk consumption is not associated with osteoporosis risk (relative risk [RR], 1.08; 95% CI, 0.52-2.24) or hip fracture (RR, 0.93; 95% CI, 0.75-1.15).
    • Every additional 200 g/day milk consumption was linearly associated with 9% higher risk for hip fracture (RR, 1.09; 95% CI, 1.07-1.11).
    • Total dairy is not associated with osteoporosis risk (RR, 0.82; 95% CI, 0.56-1.18) or hip fracture (RR, 0.90; 95% CI, 0.73-1.11).
  • Cross-sectional/case-control studies:
    • Milk consumption is not associated with lower osteoporosis risk (RR, 0.79; 95% CI, 0.57-1.08), but is associated with lower hip fracture risk (RR, 0.75; 95% CI, 0.57-0.99).
    • Total dairy is associated with lower osteoporosis risk (RR, 0.63; 95% CI, 0.55-0.73), but is not associated with lower hip fracture (RR, 0.86; 95% CI, 0.53-1.38).

Limitations

  • Heterogeneity across studies in dietary assessment tools.

Please confirm your acceptance

To gain full access to GPnotebook please confirm:

By submitting here you confirm that you have accepted Terms of Use and Privacy Policy of GPnotebook.

Submit