MMWR: opioid use disorder rate increasing among pregnant women

  • Haight SC & al.
  • MMWR Morb Mortal Wkly Rep
  • 10 Aug 2018

  • curated by Elisabeth Aron, MD, MPH, FACOG
  • Clinical Essentials
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Takeaway

  • Rates of opioid use disorder more than quadrupled between 1999 and 2014 in pregnant women admitted for hospital delivery.

Why this matters

  • Increasing trends in opioid use likely represent both increased use and increased screening and reporting.
  • Opioid use disorder during pregnancy adds to the risk for preterm labor, stillbirth, neonatal abstinence syndrome, and maternal mortality.

Key results

  • The national prevalence of opioid use disorder among pregnant women increased from 1.5 cases per 1000 delivery hospitalizations to 6.5 cases per 1000 delivery hospitalizations, with an average annual increase of 0.4 per 1000 delivery hospitalizations (P<.05>
  • There was geographic variation in rates (0.7 per 1000 delivery hospitalizations in District of Columbia and 48.6 per 1000 delivery hospitalizations in Vermont) in 2014.
  • Rates rose more rapidly in Maine, New Mexico, Vermont, and West Virginia.

Study design

  • Women using opioids between 1999 and 2014 were identified from national databases, based on ICD codes.
  • Funding: None disclosed.

Limitations

  • Not all states provide data to these databases; results may underrepresent opioid use.
  • Opioid use disorder may be underreported.

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