New European wide survey of CCRE to help improve targeting of control measures

  • European Antimicrobial Resistance Genes Surveillance Network
  • European Centre for Disease Prevention and Control
  • 28 May 2019

  • curated by Priscilla Lynch
  • Medical News
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The European Antimicrobial Resistance Genes Surveillance Network (EURGen-Net) has gone to tender for a European-wide survey of carbapenem- and/or colistin-resistant Enterobacteriaceae (CCRE).

EURGen-Net is a new surveillance network of the European Centre for Disease Prevention and Control (ECDC) with the objective to establish genomic-based surveillance of multidrug-resistant bacteria of public health importance.

The first step in this direction is the CCRE survey, which will complement the phenotypic antimicrobial resistance data available from the European Antimicrobial Resistance Surveillance Network (EARS-Net) with genomic information to identify high-risk clones and gain a more detailed understanding of transmission pathways.

The CCRE survey results are intended to inform national and European level risk assessment and decision-making for better targeting of control measures.

During a six-month period, hospitals and their associated clinical microbiology laboratories in 37 European countries are collecting carbapenem- and/or colistin-resistant Klebsiella pneumoniae and Escherichia coli isolates, as well as corresponding susceptible comparator isolates, based on a scheme that takes into account the countries’ population and geographic structure. The strain collection is primarily intended for up to 6000 isolates collected during the CCRE survey.

An additional strain collection of up to 3000 isolates of Acinetobacter baumannii for a similar carbapenem-resistance survey is planned for 2020/21.

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