New obesity guidelines underscore multifaceted approach

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  • The guidelines outline how to develop a comprehensive plan for the real-world management of obesity, including screening, diagnosis, evaluation, selection of therapy, treatment goals, and individualization of care.

Key results

  • The guidelines were jointly developed by the American Association of Clinical Endocrinologists and the American College of Endocrinology.
  • They address 9 clinical questions with 123 numbered recommendations and 160 specific statements.
  • Overall, 53.1% of the statements are strong (Grade A), 30.0% are intermediate (Grade B), 6.9% are weak (Grade C), and 10.0% are based on expert opinion (Grade D).
  • 83.1% of statements are based on strong or intermediate levels of scientific substantiation, defined as a best evidence level of 1 or 2.
  • The guidelines endorse obesity as a complex, adiposity-based chronic disease.
  • Optimal management targets both the adiposity and weight-related complications to improve patients’ overall health and quality of life.

Study desig...