- A nationally representative Norwegian cohort has found no relationship between the use of skincare products and endometrial or breast cancer.
Why this matters
- Use of skincare products is widespread, and some of them contain endocrine-disrupting chemicals that have been linked to hormonal cancer, such as breast and endometrial cancer.
- Findings will be reassuring to patients using skincare products.
- Prospective, population-based nationally representative cohort, the Norwegian Women and Cancer cohort (n=106,978), with linkage to the Cancer Registry of Norway.
- Skincare products usage was assessed by questionnaire at baseline.
- Funding: The Arctic University of Norway.
- Mean follow-up, 10.7 years.
- 3408 were diagnosed with breast cancer, 681 with endometrial cancer.
- No association between frequent/heavy skincare products use vs non/light use at baseline and premenopausal breast cancer (HR, 1.10; 95% CI, 0.92-1.32).
- No association between baseline skincare products and postmenopausal breast cancer (heavy vs light use; HR, 0.87; 95% CI, 0.65-1.18).
- Frequent vs light (HR, 0.97; 95% CI, 0.88-1.07).
- No association between baseline skincare products and endometrial cancer (frequent/heavy vs non/light; HR, 0.97; 95% CI, 0.79-1.20).
- No differences in effect were seen across the estrogen receptor (ER) status (.58≤Pheterogeneity≤.99).
- Observational design.
- No details about the content of skincare products.