No link between skincare products and endometrial, breast cancer says Norwegian study

  • Environ Health

  • curated by Miriam Davis, PhD
  • Univadis Clinical Summaries
Access to the full content of this site is available only to registered healthcare professionals. Access to the full content of this site is available only to registered healthcare professionals.

Takeaway

  • A nationally representative Norwegian cohort has found no relationship between the use of skincare products and endometrial or breast cancer.

Why this matters

  • Use of skincare products is widespread, and some of them contain endocrine-disrupting chemicals that have been linked to hormonal cancer, such as breast and endometrial cancer.
  • Findings will be reassuring to patients using skincare products.

Study design

  • Prospective, population-based nationally representative cohort, the Norwegian Women and Cancer cohort (n=106,978), with linkage to the Cancer Registry of Norway.
  • Skincare products usage was assessed by questionnaire at baseline.
  • Funding: The Arctic University of Norway.

Key results

  • Mean follow-up, 10.7 years.
  • 3408 were diagnosed with breast cancer, 681 with endometrial cancer.
  • No association between frequent/heavy skincare products use vs non/light use at baseline and premenopausal breast cancer (HR, 1.10; 95% CI, 0.92-1.32).
  • No association between baseline skincare products and postmenopausal breast cancer (heavy vs light use; HR, 0.87; 95% CI, 0.65-1.18).
    • Frequent vs light (HR, 0.97; 95% CI, 0.88-1.07).
  • No association between baseline skincare products and endometrial cancer (frequent/heavy vs non/light; HR, 0.97; 95% CI, 0.79-1.20).
  • No differences in effect were seen across the estrogen receptor (ER) status (.58≤Pheterogeneity≤.99).

Limitations

  • Observational design.
  • No details about the content of skincare products.