Non-HDL-C levels more relevant than LDL-C in stable coronary artery disease | J Clin Lipidol.
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Non–HDL-C, in comparison to LDL-C, appears to be more relevant to atherogenic lipoprotein subfractions in patients with stable coronary artery disease, thus supporting the idea that it may be better in assessing cardiovascular risk.
Cross-sectional study in 351 consecutive patients with stable coronary artery disease patients without lipid-lowering therapy.
The LDL and HDL separations were performed using the Lipoprint System.
The cholesterol concentrations of LDL (large, medium, and small) and HDL (small) particles were increased (all P < .001) by non-HDL-C or LDL-C quartiles.
The mean LDL particle size and cholesterol concentrations of HDL (large) were decreased (both P < .001) by non-HDL-C quartiles.