- A 2-week, home-based, multimodal prehabilitation program significantly improves functional capacity after video-assisted thoracoscopic surgery (VATS) lobectomy for NSCLC.
- The preoperative program included exercise, respiratory training, nutrition supplement, and anxiety reduction.
Why this matters
- Prior research suggests higher morbidity and mortality in patients with poor physical functional capacity after lung surgery.
- Randomized controlled trial.
- 73 patients with stage I-III NSCLC participated in a prehabilitation program (n=37) or received usual care (control group; n=36) before VATS lobectomy.
- Funding: None.
- At 30 days postsurgery, 6-minute walk distance (6MWD) was 21.5 m above baseline in the prehabilitation group, but declined by 36.1 m in the control group.
- 89% of patients in the prehabilitation group vs 36% pf those in the control group performed the same or better vs baseline.
- Prehabilitation improved perioperative 6MWD by 60.9 m vs the control group (P<.001>
- Forced vital capacity (FVC) was significantly better in the prehabilitation group (mean difference between groups, 0.35 L; P=.021).
- No significant differences between groups in postoperative complications, mortality, median length of stay, chest tube duration, disability, or lung function, except for FVC.
- Small sample size.