NSCLC: women more likely to be readmitted after lobectomy

  • Nelson DB & al.
  • Ann Thorac Surg
  • 14 Aug 2018

  • curated by Kelli Whitlock Burton
  • Univadis Clinical Summaries
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Takeaway

  • Women who undergo lobectomy for stage I NSCLC are significantly more likely than men to be readmitted after emergency department (ED) visits within 30 days of their index hospital discharge.

Why this matters

  • The differences in perioperative and short-term outcomes between men and women undergoing lung cancer surgery are not well understood.

Study design

  • 559 patients underwent lobectomy or sleeve lobectomy from 2010 to 2015 for clinical stage I NSCLC.
  • 206 propensity-matched male-female pairs.
  • Funding: None disclosed.

Key results

  • Pulmonary, gastrointestinal, bleeding, and wound complications were similar between sexes, but men had more cardiovascular complications (18% vs 8%; P=.004), and there were no differences in length of stay.
  • Rate of ED visits within 30 and 90 days of discharge was similar between sexes, but women were more likely to be readmitted after an ED visit within 30 days (67% vs 36%; P=.038) and 90 days (58% vs 33%; P=.053).
  • Reasons for ED visits included fever, gastrointestinal complaints, pain control, shortness of breath, urinary retention, and wound evaluation, with no difference between sexes in the rate of presenting symptom (P=.478) or time duration from discharge and presentation to ED (P=.650).

Limitations

  • Retrospective, single-center study.

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