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Clinical Summary

Obsessive-compulsive disorder: a 3-week inpatient treatment is effective

Takeaway

  • A 3-week specialised inpatient programme was effective and produced good response rates in patients with obsessive-compulsive disorder (OCD) who did not respond satisfactorily to the standard outpatient treatment.
  • Better relapse prevention interventions are however needed.

Why this matters

  • First study to investigate long-term (6 months) outcome of brief specialised inpatient treatment programme.

Study design

  • 187 adult patients with OCD who did not respond satisfactorily to the standard outpatient treatment received a 3-week specialised inpatient treatment.
  • Funding: Universities of Bergen, Oslo, Tromsø; the Norwegian University of Science and Technology (Trondheim).

Key results

  • 166 patients completed the treatment.
  • At discharge, 79.7% were treatment responders and 5.3% partial responders.
  • At 6-month follow-up, 61.5% were treatment responders and 8.0% partial responders.
  • No significant difference was observed between antidepressant users vs nonusers with respect to Yale Brown Obsessive-Compulsive Scale (Y-BOCS) posttreatment score (P=.501).
  • Pretreatment level of obsessive-compulsive symptoms (Y-BOCS) was the only significant predictor of relapse (regression coefficient, 0.17; P=.003).

Limitations                                                                                

  • Open-label design.

References


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