- Pain intensity from knee osteoarthritis was significantly higher in patients with diabetes, even after adjustment for age, BMI, and radiographic status.
Why this matters
- This study may be the first to identify a link between arthritic knee pain level and diabetes.
- Cross-sectional study on participants from osteoarthritis initiative was assessed.
- Aged 45-79 years: with diabetes, n=202; without diabetes, n=2279.
- Knee injury and Osteoarthritis Outcome Score (KOOS), numerical rating scale (NRS).
- Medical Outcomes Study Short Form 12 (SF-12).
- Center for Epidemiological Studies-Depression Scale (CES-D).
- Funding: None.
- Patients with vs without diabetes had worse scores (adjusted for BMI, osteoarthritis severity, age, and sex) on:
- KOOS (β, −4.72; P<.001>
- NRS (β, 0.42; P=.031).
- SF-12 physical (β, −3.49; P<.001>
- SF-12 mental health summary score (β, −1.42; P=.016).
- CES-D (β, 1.08; P=.035).
- Self-reported data.
- Between-group difference was attenuated when adjusting for confounders.