- The use of prostaglandins for cervical ripening did not increase risk for uterine rupture in women with 1 prior cesarean delivery (CD).
Why this matters
- The risk for uterine rupture in a woman with a previous CD has been reported to be 0.5%-1.0%.
- The use of prostaglandins in a woman with a prior CD has been discouraged in the United States because of concern for increased uterine rupture risk.
- No significant differences in rates of vaginal delivery, CD, bleeding requiring transfusion, 5-minute Apgar score ≤7, or neonatal death between groups.
- 1 case of uterine rupture in each group.
- 1 case of uterine scar dehiscence diagnosed during repeat CD.
- Prospective cohort study.
- Women with a parity of ≥5 with 1 prior CD undergoing induction of labor (IOL) with 1 mg PGE2 gel (n=96) compared with women without prior CD undergoing IOL with 1 mg PGE2 gel (n=104).
- Rates of successful IOL, repeat CD, uterine scar rupture or dehiscence, and neonatal outcomes compared.
- Funding: None disclosed.
- Small number of patients because of restrictive inclusion criteria.