Parkinson’s disease tied to risk for sexual dysfunction in men

  • Zhao S & al.
  • J Sex Med
  • 14 Feb 2019

  • curated by Sarfaroj Khan
  • UK Clinical Digest
Access to the full content of this site is available only to registered healthcare professionals. Access to the full content of this site is available only to registered healthcare professionals.

Takeaway

  • This meta-analysis suggests that men with Parkinson’s disease (PD) are more likely to experience sexual dysfunction (SD) than those without PD.
  • Association between PD and SD is non-significant in women.

Why this matters

  • Findings suggest that patients with PD should be routinely assessed for sexual functioning, especially men.

Study design

  • After a search across electronic databases, 11 observational studies involving 30,150 patients with PD and healthy control individuals (mean age 54.6-75.1 years) met eligibility criteria.
  • Funding: The Science and Technology Planning Project of Guangdong Province.

Results

  • The pooled results of 7 studies revealed that men with PD were at increased risk for SD vs the control group (relative risk [RR], 1.79; P=.001; I2, 73.2%).
  • There was no significant association between PD and SD in women (3 studies; RR, 1.3; P=.469; I2, 80.0%).
  • The pooled results of 3 studies showed a positive association between PD and SD (RR, 1.74; P=.004)
  • The GRADE profiler showed that the overall quality of the evidence was low in studies including men and very low in studies including women.

Limitations

  • Heterogeneity among included studies.
  • Stratification analyses based on disease duration not performed.

Please confirm your acceptance

To gain full access to GPnotebook please confirm:

By submitting here you confirm that you have accepted Terms of Use and Privacy Policy of GPnotebook.

Submit