PCOS: mental health screens recommended

  • Dokras A & al.
  • Fertil Steril
  • 1 May 2018

  • curated by Jim Kling
  • Clinical Essentials
Access to the full content of this site is available only to registered healthcare professionals. Access to the full content of this site is available only to registered healthcare professionals.

Takeaway

  • According to the Androgen Excess-Polycystic Ovary Syndrome Society, patients newly diagnosed with polycystic ovary syndrome (PCOS) should be screened for depression, anxiety, QoL, and eating disorders.

Why this matters

  • PCOS has recently been recognized as a multisystem disorder with various comorbidities.
  • General recommendations for population-based mental health screenings do not consider patients with PCOS to be an at-risk group, despite several meta-analyses that have shown heightened risk for depressive and anxiety symptoms.

Study design

  • This study includes systematic analysis and position paper from the Androgen Excess-PCOS Society Board.
  • Funding: None disclosed.

Key results

  • Reports from meta-analysis suggested:
    • Increased depression scores in PCOS vs control group (meta-analysis 10 studies; OR, 4.03; P<.01>
    • Increased risk for high (OR, 5.62; 95% CI, 3.22-9.80) and moderate and severe (OR, 5.38; 95% CI, 2.28-12.67) anxiety scores.
  • An increased risk for eating disorders was also reported in PCOS vs the control group (12.16% vs 2.83%; OR, 4.75; 95% CI, 1.36-16.58).
  • Health-related QoL is consistently reduced in the PCOS group vs in the control group.

Limitations

  • Small study size.
  • Interview-based confirmation not performed for depression.

Coauthored with Chitra Ravi, MPharm

Please confirm your acceptance

To gain full access to GPnotebook please confirm:

By submitting here you confirm that you have accepted Terms of Use and Privacy Policy of GPnotebook.

Submit