- According to the Androgen Excess-Polycystic Ovary Syndrome Society, patients newly diagnosed with polycystic ovary syndrome (PCOS) should be screened for depression, anxiety, QoL, and eating disorders.
Why this matters
- PCOS has recently been recognized as a multisystem disorder with various comorbidities.
- General recommendations for population-based mental health screenings do not consider patients with PCOS to be an at-risk group, despite several meta-analyses that have shown heightened risk for depressive and anxiety symptoms.
- This study includes systematic analysis and position paper from the Androgen Excess-PCOS Society Board.
- Funding: None disclosed.
- Reports from meta-analysis suggested:
- Increased depression scores in PCOS vs control group (meta-analysis 10 studies; OR, 4.03; P<.01>
- Increased risk for high (OR, 5.62; 95% CI, 3.22-9.80) and moderate and severe (OR, 5.38; 95% CI, 2.28-12.67) anxiety scores.
- Small study size.
- Interview-based confirmation not performed for depression.
Coauthored with Chitra Ravi, MPharm